Chemical Communications, 2020, 56, 4412 - 4415

Yan Wang, Feifei Yu, Xianzhu Luo, Mingshun Li, Linlu Zhao* and Fabiao Yu*

We establish a near-infrared two-photon fluorescent probe for the detection of CE2 with high selectivity and sensitivity. This probe exhibits low cytotoxicity and superior tissue penetration ability for evaluating the real-time activity of CE2 in living cells, in cancer tissues, and in a colon carcinoma mice model.