Multimodal Imaging

Novel organic small molecule/nanomaterial-based probes will be developed and used in cells and living models. By integrating the advantages of multimodal imaging, accurate locating of the tumor boundaries is possible, which will help to reduce trauma and has potential to be used in clinical models.

构建分子/纳米影像探针,精准标记疾病病灶,通过成像,在细胞和活体层次上直接观察药物治疗过程中病理生理变化和特征,实现热带病和肿瘤等疾病的早期诊断和治疗

Cancer Diagnosis and Therapy

Theranostic agents will be developed to integrate clinical diagnosis and treatment in single molecular carriers, e.g. nano-biomaterials, to achieve selective lesion targeting, reduced drug toxicity and prolonged drug efficacy, in order to realize early diagnosis and treatment of different cancers.

通过设计特异性探针,利用影像学分析系统,对药物治疗靶点的分子改变成像,直接评价药理作用,大大加快药物的筛选和开发。

Therapeutic Drug Monitoring

Molecular/nano-imaging probes will be developed to accurately label diseased lesions. The pathophysiological changes and characteristics during drug treatment at the cell and living model level can be directly observed by imaging, which is helpful to evaluate the pharmacological effect of new drugs, thus, greatly speed up drug screening and development.

发展基于有机小分子/纳米材料的探针,整合多种影像优势,利用个性化的精准治疗手段,精确定位热带病和肿瘤等疾病病灶,减少创伤,改善预后。

Microfluidic-aided Detection

Microfluidics technology is used for the rapid and efficient detection of tumor-derived extracellular vesicles in body fluids. Combined with fluorescent labeling and surface-enhanced Raman spectroscopy, a new liquid biopsy technique will be developed for non-invasive and early diagnosis of malignant tumors.

基于微流控芯片上外泌体的分离与检测,发展临床热带病、肿瘤等疾病的早期精准诊断技术和即时检测技术。